Chapter 105 Target
After Li Qingye arranged these things.
He then looked at another piece of information that Chen Jianxiong had just reported, which was about China.
After reading the relevant intelligence, Li Qingye immediately ordered: "Philip, strengthen the inspection of each control area, especially outsiders."
"Yes, boss."
Chen Jianxiong was also a little worried: "Boss, I suspect that all parts of the world have already..."
Li Qingye was even more certain than he was: "Don't doubt it, it's like finding a cockroach in your house, it must be everywhere secretly."
"Then should we increase our vigilance?" Chen Jianxiong became more and more worried.
Li Qingye thought for a while, nodded and said , "Okay, let's take advantage of this opportunity to let Luzon and Hongsawadi close off their borders for a while."
"I understand." Chen Jianxiong also knew that this was one of the few things .
As for other matters, even if the Intelligent Company has become much more powerful, it is unable to interfere in the family affairs of the five gangsters.
Suddenly, Li Qingye ordered again: "During the investigation, please send some of the target's blood samples as soon as possible. I need to study them and make preparations just in case."
"Yes, I'll arrange it right away." Chen Jianxiong had full confidence in Li Qingye's scientific research capabilities in the biological field. As long as Li Qingye was willing to take action, the Sapiens Company would at least not be completely powerless.
Looking at Chen Jianxiong who left in a hurry, Li Qingye sat on the sofa and fell into deep thought.
This sudden situation affected many of his plans.
He had originally wanted to take action against Du Jianxin's family in the near future, but now due to the suspension of flights and the increased intensity of entry screening, the soldiers who were preparing to carry out the mission could not get through for the time being.
Li Qingye was not upset about this. After all, it was impossible for everything to go smoothly.
It’s not like he doesn’t have a backup plan, it just takes a few months to adjust.
Bringing his thoughts back to reality, Li Qingye washed his face in the bathroom, then passed through the disinfection area, and then through a series of strict gates, and came to his own exclusive laboratory.
The AIDS target drug he developed for Domino and others has entered the final testing stage.
More than a dozen scumbags infected with AIDS were now being held in a special ward by the soldiers' assistants, who were monitoring the condition of these experimental subjects at all times.
"How is it going?"
Assistant No. 15 reported to him: "There is no abnormality in the body of the experimental subject, and the HIV in the body is basically undetectable, but it cannot be ruled out that it is an illusion."
HIV is very cunning and often evades the killing effects of drugs, then lies dormant, waiting until the effects of the drugs have worn off before it comes out again to cause trouble.
The target drugs developed by Li Qingye are different from traditional AIDS treatment drugs, nor are they based on the RNA technology that has only emerged in recent years.
This is a customized drug that specifically targets a specific gene target, somewhat similar to an advanced version of an RNA vaccine.
The core technology is to quickly determine the genetic sequence of the virus, and then use genetic recombination technology to create a suicide virus specifically targeting the virus, and then inject the suicide virus into the patient's body, so that the suicide virus and the virus in the patient's body will die together.
In fact, this thing is one of the derivative technologies of the gene bomb.
Therefore, this targeted drug will not cause the patient to produce antibodies in the body, but it can kill the virus and is a special specific drug.
Since it is a special drug for a specific virus, careful genetic testing of the virus in the patient's body is necessary to produce this special drug.
In other words, targeted drugs cannot be effective against all types of AIDS; they can only kill specific HIV viruses.
For example, the 15 experimental subjects in front of us all have the HIV in their bodies called AIDS, but the genes of these AIDS are different, so exclusive target drugs must be customized for each person.
If traditional technology is used, the production cost of this exclusive targeted drug would be absolutely astronomical.
Fortunately, Sapiens’ technology is different from traditional genetic technology.
The key technical points for manufacturing exclusive target drugs are as follows:
First, genetic testing technology. In this regard, the biochips and DNA storage devices currently owned by Sapiens Company use gene point determination technology that can be rapidly tested, and can produce results in seconds.
Second, using gene recombination technology, Li Qingye designed a universal virus bomb framework - [TYBD-(X)-JYZD].
This framework is very simple. The general framework consists of six parts: immune deception gene sequence, structural stability gene sequence, target chimeric gene sequence, blasting gene sequence, self-replication restriction gene sequence, and timed disintegration gene sequence.
The target chimeric gene sequence is used to quickly insert the location of the viral target gene.
Although during the target gene insertion process, only a small portion of the target gene will be successfully and completely inserted into the framework each time.
But as long as one of them is successful, the successful part can be extracted through rapid genetic testing, and then self-replication can be initiated using hormones and viral culture medium until enough target drugs are obtained.
This step usually only takes about 5 to 12 hours.
In fact, a simplified version of this technology is the current RNA vaccine technology.
The advantage of targeted drugs is that they kill viruses very quickly, almost 100% of the time, leaving no time for the virus to mutate, and also preventing the virus from developing drug resistance, with almost no side effects on the patient's body.
The disadvantages are also very obvious. The patient's body cannot produce antibodies, there is a risk of secondary infection, and it cannot be used in areas without relevant supporting facilities.
This type of targeted drug is more suitable for viruses , but not for viruses such as smallpox and influenza.
The reason why it is not suitable for smallpox and influenza is not that it cannot be used, but that these viruses have the characteristics of aerosol transmission. The viruses are killed in the patient's body, but there may be other sources of infection in the surrounding environment, which can easily cause repeated infections.
Once the infection occurs repeatedly, the previous targeted drugs cannot be used for treatment. Instead, the viral genes must be retested and targeted drugs must be manufactured based on the viral gene sequences.
Although the genetic testing technology of Sapiens is very fast and very cheap, costing only a few cents per time; the raw materials for cultivating target drugs also cost only a dozen yuan.
The problem is that such repeated efforts can easily lead to information leaks and require a large amount of manpower, especially valuable professional medical manpower.
Therefore, Li Qingye will adopt two other options for aerosol-transmitted viruses such as smallpox.
One is a simplified version of targeted drug technology - RNA vaccine.
The other type is bacteriocins (i.e. antibiotics) that target universal targets.
In fact, these two technologies are not bad. At least the technology in Li Qingye's hands is more advanced than the current human RNA vaccine technology and antibiotic technology of the same type.
The principles of the two are basically the same, but Li Qingye has made upgrades and improvements.
For example, RNA vaccine technology. The full name of the technology in Li Qingye’s hands is: Composite-multi-target combined RNA vaccine technology.
Specifically, we will target the prevalent virus strains, identify more than 10 gene targets, develop several 10-target RNA vaccines, and then combine these vaccines for use together.
Faced with this kind of vaccine, even an RNA virus that mutates very quickly is no match for it.
The same is true for targeted antibiotics.
This is also the drug that Li Qingye intends to launch into the market through Qingye Group and Zhiren Company respectively.
As for exclusive targeted drugs, this technology can only be used internally on a small scale, after all, it involves gene bomb technology.